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Health News Archive 383 - Inflammation
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Magnesium Associated With Reduced Inflammation

A number of supplements, including omega-3 fish oil, krill oil, fiber, and vitamin E, have been found to decrease inflammation. A new study in the May 2006 issue of Nutrition Research has established that magnesium, found recently to help with Metabolic Syndrome, may also help reduce inflammation.

Previous research showed an inverse relationship between blood levels of magnesium and c-reactive protein (CRP), a measure of inflammation, in older women. Building upon these findings, researchers examined data on more than 10,000 patients who participated in the 1999-2002 National Health and Nutrition Examination Survey (NHANES). Specifically, researchers looked at magnesium intake and CRP levels.

The researchers found that “taking a magnesium supplement had a big effect on total intake of magnesium”. Only 21.9% of those supplementing with less than 50 mg of magnesium per day met or exceeded the RDA for magnesium, while 60.2% of those supplementing with at least 50 mg magnesium per day met or exceeded the RDA.

When looking at magnesium and inflammation, researchers found that those taking at least 50 mg of magnesium supplements daily were 22% less likely to have elevated CRP levels. Those who didn’t meet the RDA requirements for magnesium were 40% more likely to have elevated CRP levels. The fact that magnesium supplementation had an impact on the likelihood of having elevated CRP was “a key finding” in the study.

The researchers wrote “magnesium supplement intake higher than 50 mg daily is associated with a lower likelihood of elevated CRP in people with low dietary magnesium intake.”  The National Institutes of Health established the current US RDA recommendations for magnesium at 360 mg per day for men and 410 mg per day for women.

Source: King DE. Magnesium supplement intake and C-reactive protein levels in adults. Nutr Res 2006 May; 26(3): 193-196.

S. Liu, Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women, Diabetes Care 28 (2005) (6), pp. 1438–1444.

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