Discount Vitamins & Herbs

- Products by Category
- Alphabetic Product Listing

Home Go Shopping Specials Product Info Health News FAQs About Us Links Site Map

Hyaluronic Acid Center, Neptune Krill Oil & Rejuvenation Science for Doctors

HACKER SAFE certified sites prevent over 99.9% of hacker crime.

Health Guide
Men's Health
Women's Health
Senior's Health
Sports Nutrition
Diet & Weight Loss

Vitamins & Minerals


Spa Products
Anti-Aging Basics
Body Systems
Body Structure
Book Store
Pet Health

My Recommendation
My Favorite Articles
Our Most Popular
Bargain Basement

Free Samples

In-depth Info


Health News Archive 63 - Heart (continued)
<< to structure/function index 

L-Arginine Helps The Heart

L-arginine has made many health headlines purporting the amino acid's ability to reduce blood pressure, prevent plaque buildup, lower cholesterol, and increase coronary circulation. Now, research shows that the nonessential amino acid may also reduce the risk of heart disease and other cardiac events.

The study, published in a recent issue of the Journal of Nutrition, found that supplemental arginine lowers homocysteine, a toxic amino acid found in the blood that is a cardiac risk marker (2005, vol. 135, no. 2). Researchers administered 12 grams of supplemental arginine a day to 16 middle-age men suffering from hypercholesterolemia. After each dose, scientists measured blood variables of the participants at rest and during two stress tests.

At the end of the three-week study, researchers discovered that high blood levels of l-arginine were positively correlated with a reduction in homocysteine. Arginine supplementation also produced a modest decrease in blood pressure, but the reduction was not significant enough to preclude blood-pressure medication.

L-Arginine is found in a number of common foods, including meat, poultry, fish, dairy, and nuts. However, Sheila West, PhD, the study's lead author, cautions that some arginine-rich foods, such as beef, also contain high levels of saturated fats and methionine, a homocysteine-raising amino acid, and so these foods are not recommended for heart patients. Instead, increase your arginine intake by eating beans, soy, nuts, or supplements.

Pomegranate Juice Fights Heart Disease

A glass of pomegranate juice a day could be just what your cardiologist ordered. Scientists writing in the Proceedings of the National Academy of Sciences reported three key findings on the consumption of pomegranate juice:

  • Pomegranate Juice helped reduce the fatty deposit buildup from the artery walls in mice

  • Pomegranate Juice kept the cells of the human heart healthier

  • Pomegranate Juice significantly reduced the progression of atherosclerosis by 30 percent in the mice that consumed it

Pomegranates are a Middle Eastern fruit that contain crunchy seeds surrounded by juicy pulp. It is becoming increasingly popular in the United States. One nutritionist noted that while eating pomegranates is a fun experience it is also be a messy one. For this reason she claimed that pomegranate juice may be the more practical option.

Other studies have uncovered the antioxidants in pomegranate juice might be responsible for plaque reduction on artery walls and play a part in reducing oxidative stress on endothelial cells (the cells that line the blood vessels), producing a substance called nitric oxide, which helps the blood vessels relax. It was discovered that the heart cells of mice that were given pomegranate juice had a 50 percent increase in nitric oxide and nearly a 30 percent reduction in plaque.

SOURCE: Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress. de Nigris et al. PNAS.2005; 0: 50099810

Atherosclerosis is enhanced in arterial segments exposed to disturbed flow. Perturbed shear stress increases the expression of oxidation-sensitive responsive genes (such as ELK-1 and p-JUN) in the endothelium. Evidence suggests that polyphenolic antioxidants contained in the juice derived from the pomegranate can contribute to the reduction of oxidative stress and atherogenesis. The aim of the present study was to evaluate the effects of intervention with pomegranate juice (PJ) on oxidation-sensitive genes and endothelial NO synthase (eNOS) expression induced by high shear stress in vitro and in vivo. Cultured human coronary artery endothelial cells (EC) exposed to high shear stress in vitro and hypercholesterolemic mice were used in this study. PJ concentrate reduced the activation of redox-sensitive genes (ELK-1 and p-JUN) and increased eNOS expression (which was decreased by perturbed shear stress) in cultured EC and in atherosclerosis-prone areas of hypercholesterolemic mice. Moreover, oral administration of PJ to hypercholesterolemic mice at various stages of disease reduced significantly the progression of atherosclerosis. This experimental study indicates that the proatherogenic effects induced by perturbed shear stress can be reversed by chronic administration of PJ. This approach may have implications for the prevention or treatment of atherosclerosis and its clinical manifestations.

Alpha-linolenic Acid Reduces Risk of Cardiovascular Disease

Alpha-linolenic acid (ALA) reduces cardiovascular disease (CVD) risk, possibly by inhibiting vascular inflammation and endothelial activation, according to a study published in the November issue of The Journal of Nutrition (134, 11:2991-2997, 2004) (

The researchers assessed inflammatory markers and lipid and lipoprotein levels in 23 hypercholesterolemic subjects fed two diets low in saturated fat and cholesterol and high in polyunsaturated fatty acids compared with the average American diet (AAD). The first of these two diets--the alpha-linolenic acid diet (ALA Diet)--provided 17 percent of its energy from polyunsaturated fatty acids (PUFAs) (10.5 percent LA; 6.5 percent ALA), while the second of the two diets--the linolenic acid diet (LA Diet)--provided 16.4 percent of its energy from PUFA (12.6 percent LA; 3.6 percent ALA); the AAD provided 8.7 percent of its energy from PUFAs (7.7 percent LA; 0.8 percent ALA). The ALA Diet decreased the serum concentration of a protein indicative of acute inflammation, whereas the LA Diet tended to decrease this concentration. Although both high-PUFA diets similarly decreased intercellular cell adhesion, the ALA Diet decreased vascular cell adhesion and endothelial activation more than the LA Diet. Both high-PUFA diets similarly decreased serum total cholesterol, low-density lipoprotein (LDL) cholesterol and triglycerides. The ALA Diet decreased high-density lipoprotein (HDL) cholesterol and the primary protein constituent of HDL, compared with the AAD.

The researchers concluded ALA appears to decrease CVD risk beyond its lipid-lowering effects by inhibiting vascular inflammation and endothelial activation.


Omega-3 Alpha-linolenic Acid Helps Protect Women from Cardiac Death

The American Heart Association's Scientific Sessions 2004 was the site of a presentation on November 8 of the findings of Harvard researchers that higher dietary levels of alpha-linolenic acid appear to help protect women from dying of heart disease and sudden cardiac death. Alpha-linolenic acid (ALA) is an omega-3 fatty acid found in flaxseed, canola oil, green leafy vegetables and other foods.

The team studied dietary information obtained from the Nurse's Health Study, which included 76,763 women. During the study's sixteen year follow-up, 1,325 women experienced a nonfatal heart attack, 169 underwent sudden cardiac death and 564 died from coronary artery disease.

Alpha-linolenic acid intake was found to range from 0.7 grams per day to 1.5 grams per day. Women whose intake was in the top one-fifth of participants were discovered to have a 46 percent lower risk of dying from sudden cardiac death compared to those in the lowest fifth.  Their risk of dying from coronary heart disease was 21 percent lower.

Dr Christine M. Albert, MD, assistant professor of medicine at Harvard University Medical School, and the study's lead author, explained the team's findings: "In this study, we examined whether ALA was associated with a lower risk of dying from heart disease or sudden cardiac death, which is death resulting from an abrupt loss of heart function. Sudden cardiac death is usually the result of a fatal rhythm disturbance. So, if this fat were to prevent sudden cardiac death, it would support the hypothesis that these oils were preventing fatal arrhythmias.“

"A clinical trial that randomly assigns people to ALA supplements or to a diet high in ALA would be needed to know for sure that ALA lowers risk of coronary heart disease and sudden cardiac death," Dr Albert added.  

back to top

Featured Products
Our price:
  Pomegranate Juice Concentrate
Our price:
  Flaxseed Oil
Our price:

Benfotiamine - Calcium - Coral Calcium - Ester-C - Folic Acid - Silicon - Strontium - Vitamin A - Vitamin B6 - Vitamin B12 - Vitamin C - Vitamin D - Vitamin E - Vitamin K

5-HTP - 7-Keto DHEA - Acai - Acetyl L-Carnitine  - Ageless Face, Ageless Mind - AHCC - Albizzia - Alpha-Lipoic Acid and R-Lipoic Acid - Aronia from Chokeberry - Astaxanthin - Avemar - Bacopa - Beta Glucan - Bilberry - Bioperine - Butterbur - Cetyl Myristoleate (CMO) - Chlorella: Sun, Yaeyama - Cinnamon - CLA - Coconut Oil - CoEnzymeQ10 - Curcumin from Turmeric - DHA Neuromins - Digestive Enzymes - Echinacea - Epicor -FenugreekFrench Maritime Pine Tree Bark - Garlic - Ginkgo Biloba -Glucosamine & Chondroitin - Goji Berry - Goldenseal - Grape Seed Extract - Green Tea - Guggulow - Hoodia - Horse Chestnut - Human Growth Hormone (HGH) - Hyaluronic Acid - Hydrogen (H-): The Fuel of Life - IP-6 - Krill Oil - Kudzu - L-Arginine - L-CarnitineL-Carnosine - L-Methylfolate - L-Tyrosine - Lutein - Lycopene - Mangosteen - Milk Thistle - Modified Citrus Pectin (MCP) - MSM - Mushrooms - N-Acetyl Cysteine (NAC) - Nattokinase - Neptune Krill Oil - Oil of Oregano - Oligonol - Omega-3 - DHA, EPA - Pepsin GI - Phosphatidyl Serine (PS) - Pinolenic Acid - Policosanol - Pomegranate - Prevagen - Probiotics - Probiotic Bacillus Coagulans - Psyllium Fiber - PycnogenolQuercetin - Red Yeast Rice - ReloraResveratrol - Rhodiola Rosea - Ribose - SAM-e - Saw Palmetto - Shower Water Filter - St. John's Wort - Stevia - Sytrinol - Thymic Protein AUbiquinol - Valerian - Vinpocetine

Age-Related Macular Degeneration - Air Pollution - Albizzia Helps Reduce Anxiety and Stress - Alzheimer Studies - Anxiety & Stress - Attentive Child - ADD, ADHD - Calorie Restriction Diet - Candida - Colon Cancer, Colitis, IBD - COX-2, Ibuprofen Side Effects, and Pain Management - Energy - Enzymes Support Digestion - Erectile Dysfunction - Gray Hair and Balding - Hair Growth and Male Pattern Baldness - Hearing - Homocysteine - Inflammation and Weight Loss - Immune - Life Force Multiple - Liver - Menopause - Men's Fertility - Mercury Cleansing - Milk Thistle and Liver Disease - Minor Pain and Inflammation - Omega-3 - Ultra Purity CO2 vs. Molecular Distillation - ORAC - Osteoporosis - Pain Relief - Parkinson's Disease CoenzymeQ10? - The Perricone Weight-Loss Diet - Relora Cortisol and Stress-Induced Eating - Senior's Health - Side Effects of Lipitor®, Zocor® and Statin Drugs  - The Sinatra Solution: for Heart Disease - Sinus and Allergy - St. John's Wort - Prozac® - Syndrome X - Tinnitus - Transitions for Menopause - Varicose Veins and Spider Veins  - The Wrinkle Cure for Youthful Skin

Home | Specials | Product Info | Old Health News | FAQs | About us | Blog | Links | Links2 | Links3 | Sitemap | Contact us
Alphabetic Product Listing | Products by Category | Links4 | Links5
TOLL FREE: 800-401-9186

View Cart

Terms of Use | Privacy Policy | Terms and Conditions of Sale | Disclaimer

Copyright © 2001-2010, Discount Herbs & Vitamins, Inc. All rights reserved.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Please consult a qualified medical practitioner for medical advice.